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Non-motor symptoms: Impulse control disorders and dopamine dysfunction in Parkinson's disease

Published on June 29, 2023   28 min

Other Talks in the Series: Parkinson's Disease

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0:00
My name is Antonio P. Strafella, and I'm a professor of neurology at the University of Toronto. The topic of my presentation today will be on the impulse control disorders and dopamine dysfunction in Parkinson disease.
0:17
These are my disclosures and I don't have any specific commercial interest in relation to my presentation.
0:25
The objective of today's presentation will be to describe the role of dopamine in behavioral complications in Parkinson's disease. To describe as well how neuroimaging is helping us to understand these complications and to describe receptor abnormalities and neural network changes involved with these behavioral complications in Parkinson's disease.
0:56
The recent developments in the field of molecular imaging is allowing us to investigate new frontiers in the field of Parkinson disease in atypical Parkinson's disease. Today, in our research center, we are able to image different neurotransmitters in the structures of the brain involving the dopaminergic system, but also as well, the serotonergic system and the cholinergic system. To image these different networks in our brain, we have at our disposal presynaptic and postsynaptic radiotracers as potential biomarkers. The focus, of course, today will be mostly on those imaging biomarkers for the dopaminergic system.
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Non-motor symptoms: Impulse control disorders and dopamine dysfunction in Parkinson's disease

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