Henry Stewart Talks

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Talks (186) Series (31)
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TALKS PUBLISHED/UPDATED IN THE LAST TWELVE MONTHS
October 2014
1. Role of virus infection in asthma - Part 2 (27 mins)
Play '1. Role of virus infection in asthma - Part 2'
SpeakersProf. Sebastian Johnston  –  Imperial College London, UK
Series Advances in Asthma
Relevant
    extract
Role of viruses in development of asthma - Association between early life severe lower respiratory viral illness and later development of asthma - Is this association due to a common risk factor, a... more More info
2. Airway macrophages in health and disease (35 mins)
Play '2. Airway macrophages in health and disease'
SpeakersProf. Tracy Hussell  –  University of Manchester, UK
Series Macrophage Heterogeneity and Function
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    extract
Regulation of airway macrophages - CD200 knockout mice - Changes in airway macrophages due to infections - Co-stimulation of macrophages - MicroRNAs in TLR signaling - TAM receptors - Hyaluronic ac... more More info
3. The challenge of developing drugs for neglected parasitic diseases (27 mins)
Play '3. The challenge of developing drugs for neglected parasitic diseases'
SpeakersProf. James Mckerrow  –  University of California San Francisco, USA
Series Small Molecule Drug Discovery
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The challenges of discovering and developing drugs for neglected tropical diseases - What is meant by a “neglected tropical disease”? - Identification of the organisms responsible for neglected tro... more More info
4. Dynamic reciprocity and wound healing (26 mins)
Play '4. Dynamic reciprocity and wound healing'
SpeakersProf. Ira M. Herman  –  Tufts University, USA
Series Wound Healing
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    extract
Influences of the wound micro-environment to either foster and sustain wound healing or impede wound closure - Matrix-associated signals govern tissue responses - The Dynamic reciprocity paradigm ... more More info
5. Protein degradation and defense against neurodegenerative disease part 1 of 2 (39 mins)
Play '5. Protein degradation and defense against neurodegenerative disease part 1 of 2'
SpeakersProf. Alfred Goldberg  –  Harvard Medical School, USA
Series Protein Homeostasis
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    extract
Neurodegenerative diseases with inclusion bodies associated with ubiquitin and proteasomes - Abnormal proteins rapidly degraded in cells - The ubiquitin-proteasome pathway - Ubiquitin ligases impor... more More info
6. Protein degradation and defense against neurodegenerative disease part 2 of 2 (42 mins)
Play '6. Protein degradation and defense against neurodegenerative disease part 2 of 2'
SpeakersProf. Alfred Goldberg  –  Harvard Medical School, USA
Series Protein Homeostasis
Relevant
    extract
The 26S proteasome - The 20S proteasome - Proteasome inhibitors - PS-341 - Proteasome inhibitors in multiple myeloma - Structures of the archaeal PAN ATPase-20S complex and the eukaryotic 26S prote... more More info
7. Skin innervation (27 mins)
Play '7. Skin innervation'
SpeakersProf. Martin Schmelz  –  Mannheim Heidelberg University, DE
Series Skin Biology
Relevant
    extract
Physiology of skin senses - Touch, temperature, itch and pain - Crosstalk between neurons and keratinocytes - Neuronal sensitization as basis for chronic itch and pain more More info
8. Wound bed preparation and TIME (66 mins)
Play '8. Wound bed preparation and TIME'
SpeakersProf. David Leaper  –  Cardiff University, UK
Series Wound Healing
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    extract
TIME acronym for managing wound bed preparation 10 years old; needs updating - Awareness of evidence based medicine and need for more quality research - Guidelines still needed; depend on best avai... more More info
9. Biofilm based wound care (42 mins)
Play '9. Biofilm based wound care'
SpeakersDr. Randall Wolcott  –  Southwest Wound Clinic, USA
Series Wound Healing
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    extract
Biofilm in nature - Host biofilm development - Bacterial biofilm & wound healing - Molecular mechanisms of senescence - Planktonic vs. biofilm bacteria - Medical biofilms - Biofilm defences - Antib... more More info
10. Negative pressure wound therapy: mechanisms of action and clinical uses (32 mins)
Play '10. Negative pressure wound therapy: mechanisms of action  and clinical uses'
SpeakersProf. Dennis P. Orgill  –  Harvard University, USA
Series Wound Healing
Relevant
    extract
History and Technology Transfer - Biology of Stretching Skin - Primary Mechanisms of NPWT: Macrodeformation, Microdeformation, Fluid removal, Moist wound environment - Secondary Mechanisms: Angioge... more More info
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