Henry Stewart Talks

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Talks (185) Series (29)
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TALKS PUBLISHED/UPDATED IN THE LAST TWELVE MONTHS
November 2014
1. Genetics of early onset Alzheimer's disease (35 mins)
Play '1. Genetics of early onset Alzheimer's disease'
SpeakersDr. Ekaterina Rogaeva  –  University of Toronto, Canada
Series Alzheimer's Disease
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Role of amyloid precursor protein (APP) in Alzheimer's Disease (AD) - Presenilins as AD causing genes - Phenotypic heterogeneity in cases with presenilin mutations - Gene-gene interactions in patie... more More info
2. Gammaretroviral vectors: biology, design and applications (44 mins)
Play '2. Gammaretroviral vectors: biology, design and applications'
SpeakersProf. Axel Schambach  –  Hannover Medical School, Germany
Series Gene Transfer and Gene Therapy
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The biology of retroviruses: genome & particle organization, retroviral life cycle - Retroviruses as evolutionary adapted vehicles to deliver genetic information - From the virus to the retroviral ... more More info
UG 
3. Population genetics (34 mins)
Play '3. Population genetics'
SpeakersDr. Murray P. Cox  –  Massey Univeristy, New Zealand
Series Introduction to Human Genetics
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Studying human evolution using population genetics - The history of population genetics - Demographic models - DNA datasets - Example genealogies - Calculating summary statistics (number of polymor... more More info
UG 
4. The Beta-Globin Locus (35 mins)
Play '4. The Beta-Globin Locus'
SpeakersDr. Ann Dean  –  National Institutes of Health, USA
Series Eukaryotic Gene Regulation
Epigenetics, Chromatin, Transcription and Cancer
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The globin loci encode hemoglobin subunits - Erythrocytes & hemoglobin - Human globin genes and hemoglobins - Globin gene expression during development - Globin gene structure - Sickle cell disease... more More info
5. Vitiligo: in vivo and in vitro evidence for epidermal ROS/RNS-mediated regulation / dysregulation (37 mins)
Play '5. Vitiligo: in vivo and in vitro evidence for epidermal ROS/RNS-mediated regulation / dysregulation'
SpeakersProf. Karin U Schallreuter  –  University of Greifswald, Germany
Series Skin Biology
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Role of inherited vs. induced (tanning) skin colour - Enhanced pigmentation after sun exposure - Vitiligo and its characteristics (inherited skin colour loss) - Correct diagnosis of vitiligo via ch... more More info
6. Skin epigenetics: how chromatin regulators orchestrate skin functions (33 mins)
Play '6. Skin epigenetics: how chromatin regulators orchestrate skin functions'
SpeakersProf. Vladimir Botchkarev  –  University of Bradford, UK
Series Skin Biology
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Skin structure, functions and development - Molecular control of cell differentiation - What is epigenetics? - What controls variability of skin phenotypes? - Genes encoding keratinocyte-specific p... more More info
7. Gene therapy and virotherapy in the treatment of cancer (46 mins)
Play '7. Gene therapy and virotherapy in the treatment of cancer'
SpeakersProf. Leonard Seymour  –  University of Oxford, UK
Series Gene Transfer and Gene Therapy
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Mutations and microenvironment in cancer - The challenge of cancer gene therapy - Cancer gene therapy strategies: p53 and TNF - Virotherapy against tumour cells - Virotherapy studies with wild-typ... more More info
8. A versatile platform for multilevel modeling of physiological systems (33 mins)
Play '8. A versatile platform for multilevel modeling of physiological systems'
SpeakersDr. Yoshiyuki Asai  –  Okinawa Institute of Science and Technology (OIST), Japan
Series Systems Biology
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Multi-level modeling - Physiome database and mathematical modeling - PhysioDesigner, PHML, simulator & databases - Module and physical-quantity - Mathematical expressions in a model - Reuse of modu... more More info
9. Evolutionary tradeoffs and the geometry of gene expression space (36 mins)
Play '9. Evolutionary tradeoffs and the geometry of gene expression space'
SpeakersProf. Uri Alon  –  Weizmann Institute of Science, Israel
Series Systems Biology
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Organisms, tissues and molecules often need to perform multiple tasks - Usually no phenotype can be optimal at all tasks at once which leads to a fundamental tradeoff - We study this using the conc... more More info
10. Systems medicine and proactive P4 medicine: revolutionizing healthcare. Predictive, preventive, personalized and participatory (45 mins)
Play '10. Systems medicine and proactive P4 medicine:  revolutionizing healthcare. Predictive, preventive, personalized and participatory'
SpeakersDr. Lee Hood  –  Institute for Systems Biology, USA
Series Systems Biology
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Systems Medicine and Proactive P4 Medicine - Systems medicine has reached a tipping point - Blood is window to distinguishing health from disease - Large-scale, multiparameter, digital-age, longitu... more More info
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