Henry Stewart Talks

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Talks (185) Series (33)
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TALKS PUBLISHED/UPDATED IN THE LAST TWELVE MONTHS
December 2014
1. Pharmacometric approaches to optimize use of drugs and dialysis treatments in patients with chronic kidney disease (30 mins)
Play '1. Pharmacometric approaches to optimize use of drugs and  dialysis treatments in patients with chronic kidney disease'
SpeakersDr. Marc Pfister  –  Quantitative Solutions, USA
Series Topical Talks
Relevant
    extract
The therapeutic window - The emerging discipline of pharmacometrics - Challenges of studies in CKD patients - Pharmacometrics approaches in sexagliptin treatment - Pharmacometrics approaches in ent... more More info
2. Influence of neurotransmitter receptor variants on interactions with Psychotropic Drugs (25 mins)
Play '2. Influence of neurotransmitter receptor variants on interactions with Psychotropic Drugs'
SpeakersDr. Maria Arranz  –  Institute of Psychiatry, King's College London, UK
Series Psychopharmacogenetics
Relevant
    extract
Pharmacological treatment in psychiatry - Causes of treatment variability - Genetic influence on drug-target interactions - Pharmacological profile of psychotropics - The dopaminergic system and d... more More info
3. Tailoring psychiatric treatment using genetic information: pharmacogenetic prediction of treatment response (29 mins)
Play '3. Tailoring psychiatric treatment using genetic information: pharmacogenetic prediction of treatment response'
SpeakersDr. Maria Arranz  –  Institute of Psychiatry, King's College London, UK
Series Psychopharmacogenetics
Relevant
    extract
Pharmacological treatment in psychiatry - Causes of treatment variability - Contribution of genetic variants of the CYP enzymes to drug metabolism - Influence of genetic variance on drug treatment ... more More info
4. Vesicular release of transmitter at active zones (30 mins)
Play '4. Vesicular release of transmitter at active zones'
SpeakersProf. Stefan Hallermann  –  European Neuroscience Institute Göttingen, Germany
Series Synapses, Neurotransmitters and Receptor Channels
Relevant
    extract
Vesicular release of transmitter - Structural heterogeneity of active zones - Filamentous structures at active zones - Mechanisms & measurement of vesicular release - Fluctuation analysis - Short-t... more More info
5. Interactome networks and human disease (39 mins)
Play '5. Interactome networks and human disease'
SpeakersProf. Marc Vidal  –  Harvard Medical School, USA
Series Systems Biology
Relevant
    extract
Linear genotype-phenotype relations - Genotype and phenotype of eye color - Complex genotype-to-phenotype relationships - Cells as complex wiring diagrams of interaction - Types and properties of i... more More info
6. The evolutionary web of life (30 mins)
Play '6. The evolutionary web of life'
SpeakersProf. John Torday  –  Harbor-UCLA Medical Center, USA
Series Evolution and Medicine
Relevant
    extract
Rationale for homeostatic change as evolution - Historic perspective on homeostasis - Lung surfactant as a molecular fossil - Evolution (ontogeny + phylogeny + homeostasis) - Molecular evolutionar... more More info
7. Cannabinoid type 1 receptors in Astrocytes (37 mins)
Play '7. Cannabinoid type 1 receptors in Astrocytes'
SpeakersProf. Giovanni Marsicano  –  NeuroCentre Magendie, Bordeaux, France
Series Physiology and Pathophysiology of Neuroglia
Relevant
    extract
Mechanism of action of cannabinoid type 1 receptors (CB1) - Endocannabinoids (ECBs) and their role as retrograde neurotransmitters - The Cre/loxP system - CB1 in neurons and in astrocytes - CB1 del... more More info
8. Mitochondrial and lysosomal dysfunction in the pathogenesis of Parkinson’s disease (35 mins)
Play '8. Mitochondrial and lysosomal dysfunction in the pathogenesis of Parkinson’s disease'
SpeakersProf. Anthony Schapira  –  Department of Clinical Neurosciences, University College London, UK
Series Parkinson's Disease
Relevant
    extract
Pathogenesis of Parkinson’s disease (PD) - Mitochondria (biochemistry, DNA, proteins, turnover) - Oxidative phosphorylation and respiratory chain - Fraction of deleted mtDNA in substantia nigra (SN... more More info
9. The ERK1/2 MAPK cascade (29 mins)
Play '9. The ERK1/2 MAPK cascade'
SpeakersProf. Melanie H. Cobb  –  University of Texas Southwestern Medical Center at Dallas, USA
Series Signal Transduction via Protein Tyrosine Kinase Receptors
Relevant
    extract
MAPK cascade paradigm - Properties of the MAPK cascade - ERK1/2 in disease and development - Activation of the MAPK cascade - Structure and motifs in the cascade - Generating specificity in MAPK ... more More info
10. Pharmacometrics in tuberculosis (69 mins)
Play '10. Pharmacometrics in tuberculosis'
SpeakersProf. Charles A. Peloquin  –  University of Florida, USA
Series Topical Talks
Tuberculosis
Relevant
    extract
FDA approved drugs for tuberculosis - Non-FDA approved drugs for tuberculosis - How do antibiotics work? - Pharmacokinetics and pharmacodynamics - Pharmacodynamics of isoniazid and ethionamide - "C... more More info
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