Henry Stewart Talks

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Talks (172) Series (31)
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TALKS PUBLISHED/UPDATED IN THE LAST TWELVE MONTHS
August 2014
1. Acid-peptic diseases of the stomach and duodenum including Helicobacter pylori and NSAIDs (48 mins)
Play '1. Acid-peptic diseases of the stomach and duodenum including Helicobacter pylori and NSAIDs'
SpeakersProf. Sheila Crowe  –  Division of Gastroenterology UC San Diego, School of Medicine
Series Gastroenterology and Hepatology
Relevant
    extract
Clinical presentations of H. pylori infection - Upper GI diseases and H. pylori infections - Microbiologic factors - Epidemiology/transmission - Pathophysiologic factors - H. pylori gastritis: path... more More info
2. Inherited neuropathies (69 mins)
Play '2. Inherited neuropathies'
SpeakersProf. Mary M. Reilly  –  University College London, UK
Series The Genetic Basis of Neurological Disorders
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    extract
Inherited neuropathies - Charcot Marie Tooth disease is the commonest inherited neuropathy - Four genes out of 78 account for over 60% of the cases of CMT - Genotype / phenotype correlations explor... more More info
3. Genetics of epilepsy (41 mins)
Play '3. Genetics of epilepsy'
SpeakersProf. Sanjay Sisodiya  –  University College London, UK
Series The Genetic Basis of Neurological Disorders
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    extract
Epilepsy and genetics - Significant contribution of genetics to many epilepsies - Many types of variation, and methods to detect them - Importance of correct interpretation - Will likely revolution... more More info
4. Genetics of hereditary spastic paraplegia (34 mins)
Play '4. Genetics of hereditary spastic paraplegia'
SpeakersDr. Arianna Tucci  –  University College London, UK
Series The Genetic Basis of Neurological Disorders
Relevant
    extract
Definition and overview of Hereditary spastic paraplegia (HSP) - The motor system in HSP - HSP pathophysiology HSP - Heterogeneity of HSP - Neuropathology in HSP - Clinical features & classificatio... more More info
UG 
5. Surface-mediated targeting of lentiviral vectors (29 mins)
Play '5. Surface-mediated targeting of lentiviral vectors'
SpeakersProf. Dr. Christian Buchholz  –  Paul-Ehrlich-Institut, Germany
Series Gene Transfer and Gene Therapy
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    extract
In vivo and ex vivo gene therapy - Cell entry modes of retroviral vectors - Molecular functions of viral envelope proteins - Introduction to surface targeting - Targeting subtypes of lymphocytes an... more More info
6. Gene therapy and gene transfer: vector integration preferences and integration site analysis (50 mins)
Play '6. Gene therapy and gene transfer: vector integration preferences and integration site analysis'
SpeakersProf. Frederic Bushman  –  University of Pennsylvania, USA
Series Gene Transfer and Gene Therapy
Relevant
    extract
Introduction: human gene therapy with integrating vectors - Methods for monitoring gene transfer - HIV integration targeting - Gammaretroviral integration targeting - Analysis of vector integration... more More info
7. The host response: adaptive immune response to viral vector delivery (41 mins)
Play '7. The host response: adaptive immune response to viral vector delivery'
SpeakersProf. Roland W. Herzog  –  University of Florida, USA
Series Gene Transfer and Gene Therapy
Relevant
    extract
Gene therapy using viral vector - Risk of immune responses specific to vector or transgene product - Pre-existing immunity to viral vectors due to natural infection - Design of vectors to minimize ... more More info
UG 
8. Manufacturing viral gene therapy vectors: general approaches and challenges (36 mins)
Play '8. Manufacturing viral gene therapy vectors: general approaches and challenges'
SpeakersProf. John T. Gray  –  Audentes Therapeutics Inc., USA
Series Gene Transfer and Gene Therapy
Relevant
    extract
Manufacturing of Viral Gene Therapy Vectors - Different types of vector production systems - Concepts for the design of viral vector production cells - Specific viral vector production systems for ... more More info
UG 
9. Pathogenic mechanisms in prion disease  (32 mins)
Play '9. Pathogenic mechanisms in prion disease '
SpeakersDr. Giovanna Mallucci  –  University College London, UK
Series The Genetic Basis of Neurological Disorders
Relevant
    extract
Neurodegenerative diseases and protein misfolding disorders - Prion disease in mice to study mechanisms of neurodegeneration due to misfolded protein accumulation - Early prion neurodegenerative ch... more More info
10. Helper-dependent adenoviral vectors for gene therapy (57 mins)
Play '10. Helper-dependent adenoviral vectors for gene therapy'
SpeakersProf. Nicola Brunetti-Pierri  –  The Telethon Institute of Genetics and Medicine, Italy
Series Gene Transfer and Gene Therapy
Relevant
    extract
Overview of gene therapy vectors - Helper-Dependent Ad (HDAd) vector - Liver and lung directed gene therapy - Hemophilia B gene therapy - OTC deficiency clinical trial - Balloon occlusion catheter-... more More info
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